Licorice root extract is used in many skin care products for the face like moisturizers, anti-aging creams, and sunscreens.

It is a common ingredient found across the world and throughout history for its versatility in medicine, food, and cosmetics.

Licorice extract has many appreciable benefits and only a few potential side effects.

Find out if licorice extract is right for your custom skin care regimen!

Licorice extract (Glycyrrhiza glabra) is an oil pressed from the roots of a licorice plant.

It was used by ancient civilizations like the ancient Egyptians, Greeks, and Romans, the ancient Chinese Han Dynasty (300-200B.C.E) ^(2).

Today, licorice remains one of the most frequently used herbs in eastern holistic supplements and remedies.

Licorice root extract is an ancient, versatile, and popular ingredient in modern western skin care products as well.

Several species of licorice are used for their extracts in skin care today.

Closely related to common licorice root is (Glycyrrhiza inflata), the Chinese licorice root. they share pharmaceutical and dietary uses even though they are not the exact same species ^(3).

Licorice root extract has a variety of appreciable benefits used in skin care and in other kinds of products.

It is commonly used in moisturizers for its high concentration of beneficial moisturizing fatty acids.

Licorice root is anti-microbial, meaning it eliminates bacteria and can be used to extend shelf lives of skin care or food products.

Anti-microbials like LRE are also extremely useful in acne products.

It is also estrogenic, meaning it can be used in some hormone supplements to regulate various reproductive processes. ⁽⁵⁾

There are active antioxidants in LRE as well, meaning it is good for conditions like sun damage and other forms of hyperpigmentation. ⁽¹⁾

It is a tyrosinase inhibitor, which means it slows melanin production and treats dark spots.

The anti-inflammatories in LRE are great for soothing inflammation, irritation, or mild allergic reactions on the skin. ⁽⁵⁾

Licorice root extract is a versatile compound that is very common and useful in skin care products.

Licorice root extract is used in a variety of skin care products like:

anti-aging serums

facial peels

moisturizers

skin lighteners

sunscreens

Take the questionnaire to shop by your skin type for the best licorice oils for you!

Licorice root extract is safe for use as long as you are not pregnant while using it.

The EWG score for licorice root is "5" which is not great; but the only advisement is to avoid use during pregnancy.

An allergy to LRE is possible, but very rare.

At any other point, licorice root extract is completely safe for use and is often recommended in many skin care products.

Shop by your Baumann Skin Type to make sure licorice extract is right for you.

One study conducted in Finland showed that babies who were exposed to high amounts of ingested licorice in utero experienced a few developmental differences from a control group (17).

The children with high exposure to licorice grew to be taller, heavier, and started puberty sooner than the control.

It also appeared that the same group exposed to licorice exhibited worse memory and a higher tendency for mild learning disability (17).

To avoid any chance of developmental abnormalities, it is advised to avoid licorice root while pregnant, including in body care. products.

Many different compounds make up this versatile and beneficial extract.

Licorice root extract contains a high concentration of flavonoids like glabridins, which give the extract a yellow hue.(4)

Anywhere between 4-25% of the extract is made of glycyrrhizinic (Gli-syr-i-zi-nic) acid, depending on how the extract was refined.

Other active compounds in LRE are⁽⁴⁾:

Abscisic acid

Benzoic acid

Glycyrrhetinic acid

Glycyrrhiza polysaccharide

Isoliquiritigenin

Liquiritigenin

Liquiritin

Salicylic acid

Licorice root extract is a tyrosinase inhibitor, which means it stops your skin from producing melanin (the pigment that darkens skin color).

LRE is great for use in skin lightening products, and works more effectively alongside PAR-2 blockers like Niacinamide or other tyrosinase inhibitors like hexylresorcinol.

There are a number of effective hyperpigmentation regimens that could make great use of LRE, but it can take between 8-16 weeks to see results just like any healthy skin lightener.

Antioxidants in LRE also treat sun damage and help prevent skin cancer by eliminating free radical ions on and just beneath the skin.

Melasma is a skin pigment disorder which is most commonly treated with tyrosinase inhibitors like licorice root extract.

Melasma is common during pregnancy, but LRE is not advised for use while pregnant.

Check out this article all about treating melasma during pregnancy to find alternatives for LRE.

To make sure LRE is right for your custom skin care regimen, take the Baumann Skin Type questionnaire to shop by your skin type!

Here are some of the best products containing licorice root extract in skin care:

1. Jiang, J., Zhang, X., True, A. D., Zhou, L., & Xiong, Y. L. (2013). Inhibition of lipid oxidation and rancidity in precooked pork patties by radical?scavenging licorice (Glycyrrhiza glabra) extract. Journal of food science, 78(11), C1686-C1694.
2. (Yakugaku Zasshi. 2000;120(10):849-62).
3. (Antimicrob Agents Chemother. 2002;46(5):1226-30)
4. Abo-Samaha, M. I., Alghamdi, Y. S., El-Shobokshy, S. A., Albogami, S., El-Maksoud, E. M. A., Farrag, F., ... & El-Hack, M. E. A. (2022). Licorice Extract Supplementation Affects Antioxidant Activity, Growth-Related Genes, Lipid Metabolism, and Immune Markers in Broiler Chickens. Life, 12(6), 914.
5. Somjen, D., Knoll, E., Vaya, J., Stern, N., & Tamir, S. (2004). Estrogen-like activity of licorice root constituents: glabridin and glabrene, in vascular tissues in vitro and in vivo. The Journal of steroid biochemistry and molecular biology, 91(3), 147-155.
6. Baumann L, Saghari S. Retinoids. In: Cosmetic Dermatology: Principles and Practice, 2nd edition. L Baumann, S Saghari, E Weisberg, eds. New York: McGraw-Hill, 2009, pp. 256-262.
7. Weiss JS, Ellis CN, Headington JT, Tincoff T, Hamilton TA, Voorhees JJ. Topical tretinoin improves photoaged skin. A double-blind vehicle-controlled study. JAMA. 1988;259(4):527-32. Erratum in: JAMA 1988 Aug 19;260(7):926. Erratum in: JAMA 1988 Jun 10;259(22):3274.
8. Zasada M, Budzisz E. Retinoids: active molecules influencing skin structure formation in cosmetic and dermatological treatments. Postepy Dermatol Alergol. 2019;36(4):392-397.
9. Sorg O, Kuenzli S, Kaya G, Saurat JH. Proposed mechanisms of action for retinoid derivatives in the treatment of skin aging. J Cosmet Dermatol. 2005;4(4):237-44.
10. Park BS, Jang KA, Sung JH, Park JS, Kwon YH, Kim KJ, et al. Adipose-derived stem cells and their secretory factors as a promising therapy for skin aging. Dermatol Surg. 2008;34(10):1323-6.
11. Gibson SJ, Lindh JM, Riter TR, Gleason RM, Rogers LM, Fuller AE, et al. Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod. Cell Immunol. 2002;218(1-2):74-86.
12. Barland CO, Zettersten E, Brown BS, Ye J, Elias PM, Ghadially R. Imiquimod-induced interleukin-1 alpha stimulation improves barrier homeostasis in aged murine epidermis. J Invest Dermatol. 2004;122(2):330-6.
13. Shaw AC, Panda A, Joshi SR, Qian F, Allore HG, Montgomery RR. Dysregulation of human Toll-like receptor function in aging. Ageing Res Rev. 2011;10(3):346-53.
14. Metcalf S, Crowson AN, Naylor M, Haque R, Cornelison R. Imiquimod as an antiaging agent. J Am Acad Dermatol. 2007;56(3):422-5.
15. Altalhab S. The effectiveness of imiquimod 5% cream as an anti-wrinkle treatment: A pilot study. J Cosmet Dermatol. 2019;18(6):1729-1732.
16. Sachs DL, Voorhees JJ. Age-reversing drugs and devices in dermatology. Clin Pharmacol Ther. 2011;89(1):34-43.
17. Räikkönen, K., Martikainen, S., Pesonen, A. K., Lahti, J., Heinonen, K., Pyhälä, R., ... & Kajantie, E. (2017). Maternal licorice consumption during pregnancy and pubertal, cognitive, and psychiatric outcomes in children. American journal of epidemiology, 185(5), 317-328.