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Best anti-aging serums for men

The Best Antiaging Serums for Men

Written by: Dr. Leslie Baumann

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Time to read 7 min

To help you look as young as you feel, we have put together the top 10 anti-aging serums for men.

Take our skin type quiz to make sure you only buy the right products for your skin type. Nothing feels worse than wasting money on the wrong products!

In this top 10 list we discuss anti-wrinkle serums for men with oily, dry, combination and sensitive skin- but there is much more to that when choosing a serum. Do yourself a favor and let us guide your serum shopping by taking the quiz. We ask many questions that help guide our dermatologist recommendations so you get custom personalized advice. Our AI bot can help too!

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Match serum to your Baumann Skin Type

Consider if you will use after shaving or not

Pick serums that match your skin concerns

A retinoid is best for most of the skin types

best anti-aging serums for men

Antiaging Serums For Men

There are many face serums to treat wrinkles. But some serums are designed for menopausal skin and may have estrogen like ingredients which are not right for men. It is best to take our quiz which will ask you your age, gender, and about your habits and skin condition. Once we assign you t one of 16 skin types, we can give you suggestions that are right for your unique needs.

These are my top 10 favorite serums for men to treat wrinkles, but is it best if you take our validated quiz before you shop.

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Top 10 Antiaging Serums for Men

La Roche-Posay Redermic Anti-aging Treatment Intensive

This intensive anti-aging serum contains a stabilized form of retinol for deep wrinkle correction. It's great for targeting fine lines, wrinkles, dark spots and uneven texture. The formula is ideal for men with oily or irregularly pigmented skin. Use this serum only at night. During the day, be sure to apply sunscreen to protect newly surfaced skin cells.

Revision Skincare C+ Correcting Complex

Combat the fading of your glowing skin with this serum loaded with peptidesantioxidants and tons of Vitamin C. It helps build collagen, fade dark spots and improve skin tone and texture. The soothing formula is ideal for men with sensitive or dry skin. For optimal results, use twice daily alone or pair with a retinol cream at night.

Neocutis Bio Gel Firm Moisturizing Hydrogel

One of my favorite anti-aging serums for men with oily skin- this uniquely lightweight serum leverages an optimal formulation of skin-structure-supporting peptides, antiaging growth factors and hyaluronic acid aiming to improve sagging mature skin and wrinkled texture by targeting, filling and preventing volume loss for visibly denser, renewed firmness. This product has zero estrogenic side-effects and is fragrance free, meaning it is perfectly tailored for male use.

Alastin Restorative Skin Complex

The potent peptide complex in this serum helps support the skin's elasticity and resilience for a firmer, smoother and more youthful appearance. Its formula boosts hydration levels and absorbs quickly without leaving behind any greasy residue. It's ideal for men with sensitive skin who want anti-aging benefits but cannot tolerate traditional retinol treatments.

Defenage 8-in-1 Bioserum

This intelligent “Swiss Army knife” of a serum wields a blended arsenal of antioxidants, texture-refining alpha hydroxy acids, patented peptides and other supporting molecules to simultaneously tackle wrinkles, stubborn spots, hyperpigmentation, and sun-damage in one comprehensive formula. Your skin will feel renewed in just a few weeks. What's more, this product is great for sensitive skin types and easy to tolerate, so long as you are not allergic to niacinamide. This serum lightens spots and gives skin better texture.

Medature Encapsulated Retinol Serum

This gentle yet effective anti-aging serum uses an innovative encapsulated retinol delivery system to gradually release the active ingredients to minimize irritation and dryness. It's suitable for oily, combination, and dry types and helps smooth away fine lines while refining skin texture, shrinking pores and fading dark spots. If redness is an issue for you, introduce this product slowly at first - every third day - until you become used to it. Once your skin is comfortable enough with the use of retinoids, you can start using this product daily.

Plated SkinScience Intense Serum

Protect your skin's boyish glow with this cutting-edge top selling luxury serum that men love. It contains exosomes - tiny, naturally occurring messenger structures - to signal your skin cells to ramp up collagen production. To get the most out of this product, I recommend using it alongside vitamin C and/or retinoids- but this depends on which of the 16 skin types you are. Most men notice a visible difference within 2 weeks when used daily, but give it 8 weeks before you judge the results.

SkinCeuticals C+ AHA

The Vitamin C and glycolic acid duo packed into this breakthrough serum delivers both short and long term brightening, exfoliating and collagen boosting results specifically tailored for men with resistant skin types that can tolerate its uniquely low pH formulations. While some positive effects may appear within weeks, the full scope of benefits often unfold gradually over a 3-6 month period of consistent use, ultimately combatting dulling tone and early wrinkling. Use caution when combining with retinol, as both ingredients are highly effective exfoliants that could potentially over-dry the skin if applied simultaneously.

Sente Dermal Repair Cream

Multiple hydrating ingredients like glycerin, heparan sulfate and glucosamine fill the skin with vital moisture while smoothing out mature lines. Supported by a combination of Vitamin E and other anti-aging ingredients, this product bolsters collagen and defends against environmental stressors over time. I recommend using this product as part of your AM skin care routine. At night, use this product alongside a retinoid if you can tolerate retinoids. Good for men with rosacea and wrinkles.

SkinMedica TNS Advanced+ Serum

This one of the most advanced growth factor serums on the market. It combines two technologies into one antiaging serum.  This one is gentle enough for men with sensitive skin and to use after shaving. Works best when combined with retinoids and Vitamin C- but which products to use with it in your routine depends upon which of the 16 skintypes you are.

We hope this list of antiaging serums for men has given you more confidence that the fate of your face is still in your hands. A good antiaging product can make all the difference in the way your skin matures.

To get custom skin advice, shop by your skin type, or build a custom routine- take our skin type quiz.  You will be glad you did because it will save you so much time! You can opt in for the monthly educational emails once we know your Baumann Skin Type and if you want more info- visit us on social media including Reddit @skintypesolutions.

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Level up your skin care knowledge with medical advice from dermatologists

What is the best antiaging serum for men with dry skin?

The best serum to use depends on which of the 16 skin types you are. If you have inflammation, a serum like Plated Intense Serum or SkinMedica TNS Advanced+ Serum are good choices.

If you have dark spots that also need correcting, the Revision Skincare C+ Correcting Complex 30% or the Skinceuticals C+AHA is a good choice. 

Men with dry skin need to apply a barrier repair moisturizer such as Zerafite Wrinkle Defense Face Cream on top of any serum. 

What antiaging serum with retinol is best for men?

If you are a skin type that can tolerate retinol, start with a low strength retinol like Medature Encapsulated Retinol Serum or La Roche-Posay Redermic R Antiaging Treatment Intensive.

Where can men find the best antiaging skin care products?

To find the best antiwrinkle skin care, men should first identify which of the 16 Skin Types they are and then shop for products using their skin type.

What is the best men's face serum?

First you need to know which of the 16 skin types you are and then you need to decide if you are going to apply the serum after shaving. A good antiaging serum for men to use after shaving is Neocutis BIO GEL FIRM Moisturizing Hydrogel.https://skintypesolutions.com/products/neocutis-bio-gel-firm

Best References on Antiaging products for males:

  1. Baumann L. Antiaging Ingredients in Ch. 37 of Baumann's Cosmetic Dermatology Ed 3. (McGraw Hill 2022)
  2. Baumann, L. Ch. Cosmeceuticals and cosmetic Ingredients (McGraw Hill 2015)
  3. Baumann, L. (2018). How to use oral and topical cosmeceuticals to prevent and treat skin aging. Facial Plastic Surgery Clinics26(4), 407-413.
  4. Baumann, L. (2007). Skin ageing and its treatment. The Journal of Pathology: A Journal of the Pathological Society of Great Britain and Ireland211(2), 241-251.
  5. Baumann, L. (2005). How to prevent photoaging?. Journal of Investigative Dermatology125(4), xii.
  6. Agrawal, R., Hu, A., & Bollag, W. B. (2023). The skin and inflamm-aging. Biology12(11), 1396.
  7. Zhang, J., Yu, H., Man, M. Q., & Hu, L. (2024). Aging in the dermis: Fibroblast senescence and its significance. Aging Cell23(2), e14054.

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