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A.G.E Interrupter Advanced
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Nothing in this product works against any of your four letters, so it is safe for your skin type.
Not recommended for your sensitivity
Antiwrinkle Cream to block skin glycation
Why Dr. Baumann carries this
Written for this product
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Approved for Baumann Skin Types
- 3
- 4
- 7
- 8
- 11
- 12
- 15
- 16
Approved for 8 of the 16 Baumann Skin Types. Dr. Baumann reviews every product against all 16 types before it goes on the site.
What it is and what it does
Breakthrough corrective cream helps reverse visible signs of aging impacted by glycation and collagen decline, including fine lines and deep wrinkles. Backed by 15+ years of glycation research and expertise, A.G.E. Interrupter Advanced is a potent anti-wrinkle cream that helps correct and defend against visible signs of aging. Formulated with 18% concentrated ProxylaneTM, 4.25% wild fruit flavonoid blend of blueberry and pomegranate extracts, and 0.1% glycyrrhetinic acid, this breakthrough corrective cream is clinically proven to smooth visible lines and deep wrinkles in five facial zones targeted for aesthetic procedures.
Who it is for
Approved for 8 of the 16 Baumann Skin Types.
Key ingredients

Soothing antiaging ingredient that gives cells energy. Help prevent recurrence of dark spots and unwanted skin pigment.

Stearic Acid
Best fatty acid for barrier repair creams, eczema cream and moisturizers.

A form of Vitamin B5 that soothes and hydrates sensitive skin

Glyceryl Stearate
A combination of glycerin and stearic acid to hydrate skin. A humectant and occlusive moisturizer.

Caprylic/Capric Triglyceride
Combination of hydrating coconut oil and glycerin to moisturize skin.

Glycerin (Glycerol) is the best natural moisturizing ingredient to hydrate skin quickly. May give products a sticky feel.
Full ingredient list
Product type and skin type data
| Brand | SkinCeuticals |
|---|---|
| Product type | Facial Moisturizer |
| Size | 1.7 oz. |
| Item number | SC-MB5841 |
| Approved Baumann Skin Types | OSPW, OSNW, DSPW, DSNW, DRPW, ORPW, ORNW, DRNW |
| Recommended for these sensitivities | Acne, Redness, Stinging |
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Questions about this product
Answered by Dr. Leslie Baumann, MD, FAAD · Miami, FL · 200+ partner practices
Niacinamide is an antioxidant that reduces oxidative stress, a key driver of advanced glycation endproducts (AGE), helping protect collagen and support dermal integrity. Pomegranate extract provides polyphenol antioxidants that help neutralize reactive carbonyl species involved in advanced glycation endproducts (AGE) formation and support collagen preservation. Bilberry extract contains anthocyanins with antioxidant and carbonyl-scavenging activity that may help inhibit protein cross-linking associated with advanced glycation end products (AGE).
Hydroxypropyl Tetrahydropyrantriol is a sugar-derived molecule that helps support the skin’s extracellular matrix by stimulating glycosaminoglycans (GAGs), which bind water within the skin. It enhances hydration and improves the appearance of firmness by strengthening structural support in the dermis. The firming effect is primarily due to improved water retention and matrix support and is cosmetic and temporary with continued use needed to maintain results.
A.G.E. Interrupter Advanced includes niacinamide, pomegranate extract, and glycyrrhetinic acid, which are not in the original formula. The original formula contained 4% blueberry extract alone, while the Advanced version uses a broader wild fruit flavonoid blend including blueberry and pomegranate. The original included phytosphingosine, which is not featured in the Advanced version. The Proxylane concentration was adjusted from 30% in the original to 18% in the Advanced formula, shifting the focus toward a more comprehensive glycation and oxidative stress approach.
Reviews
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