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Peptide-Rich Defense SPF 50
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Cosmedix Peptide-Rich Defense SPF 50 – Hydrating Mineral Sunscreen with Peptides Protect your skin while supporting a more youthful-looking complexion with Cosmedix Peptide-Rich Defense SPF 50.
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What it is and what it does
Cosmedix Peptide-Rich Defense SPF 50 – Hydrating Mineral Sunscreen with Peptides
Protect your skin while supporting a more youthful-looking complexion with Cosmedix Peptide-Rich Defense SPF 50. This lightweight daily mineral sunscreen provides broad-spectrum SPF 50 protection against UVA and UVB rays while hydrating the skin and helping reduce the visible signs of aging. Formulated with peptides, antioxidants, and zinc oxide, it helps defend against environmental stressors while promoting smoother, healthier-looking skin.
Designed for daily wear, this non-greasy formula blends seamlessly into the skin, making it an ideal final step in any morning skincare routine. It layers beautifully under makeup and provides lasting hydration without feeling heavy.
Key Benefits
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Provides broad-spectrum SPF 50 UVA/UVB protection
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Helps defend against premature signs of sun-induced aging
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Hydrates and nourishes the skin
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Peptides help improve the appearance of fine lines and wrinkles
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Antioxidants help protect against environmental stressors
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Lightweight, non-greasy formula
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Layers smoothly under makeup
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Suitable for all skin types
Key Ingredients
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Zinc Oxide: Provides broad-spectrum mineral sun protection against UVA and UVB rays.
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Peptides: Help support firmer, smoother, younger-looking skin.
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Antioxidants: Help defend against free radical damage and environmental stressors.
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Hydrating Ingredients: Help maintain moisture for soft, healthy-looking skin.
How to Use
Apply generously to the face and neck as the final step in your morning skincare routine, at least 15 minutes before sun exposure. Reapply every two hours and after swimming, sweating, or towel drying for continued protection.
Cosmedix Peptide-Rich Defense SPF 50 combines high-performance mineral sun protection with anti-aging skincare benefits to help keep your skin protected, hydrated, and radiant every day.
Key ingredients

Avobenzone (Butyl Methoxydibenzoylmethane) is an oil-soluble organic sunscreen filter that provides broad-spectrum protection by absorbing UVA1 (340–400 nm) and UVA2 (320–340 nm) wavelengths, with peak absorption around 357–360 nm. Because avobenzone is photounstable, it is typically formulated with photostabilizers such as octocrylene or newer stabilizing technologies to maintain UV protection. As an oil-soluble filter, it is commonly incorporated into water-resistant sunscreen formulations. Avobenzone may cause eye stinging if it migrates into the eyes and can rarely cause allergic or photoallergic contact dermatitis in susceptible individuals. Noncomedogenic.

Oxybenzone
Oxybenzone (Benzophenone-3) is an oil-soluble organic sunscreen filter that protects against UVB (280–320 nm) and UVA2 (320–340 nm) wavelengths, with limited UVA1 coverage. It absorbs ultraviolet radiation and dissipates the energy as heat, helping prevent sunburn, photoaging, DNA damage, and photocarcinogenesis. Oxybenzone is photostable and is often combined with other UV filters to achieve broad-spectrum protection. It may cause eye stinging and can trigger allergic or photoallergic contact dermatitis in susceptible individuals. Oxybenzone is systemically absorbed after topical application, but current evidence has not demonstrated hepatotoxicity or adverse health effects at approved concentrations. Environmental concerns have been raised because laboratory studies suggest oxybenzone may contribute to coral toxicity, leading to restrictions in some region

Octyl methoxycinnamate. Sunscreen. May cause skin allergy. Don't use in ocean because may harm coral

Peptides are a diverse group of ingredients, each offering unique benefits, such as boosting collagen production, firming skin, or improving texture by coating the skin's surface. However, peptides can inactivate other ingredients, so it's crucial to use peptide-based products in the correct step of your skincare routine and ensure all ingredients are compatible. Since peptides often struggle to penetrate the skin, they work best in a routine specifically designed to enhance their absorption. To maximize their effectiveness, your entire skincare regimen should focus on optimizing penetration, maintaining stability, and minimizing reactions with incompatible ingredients.
Full ingredient list
Product type and skin type data
| Brand | Cosmedix |
|---|---|
| Product type | Sunscreen |
| Item number | COS-8520190 |
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