Acne

Cystic Acne

cystic acne
In this article
  1. Why do I get acne cysts?
  2. What is Cystic Acne?
  3. What is the white stuff that comes out of a cyst?
  4. What causes cystic acne?
  5. How to Treat Cystic Acne?
  6. Vitamins To Use if You Have Cystic Acne
  7. Vitamins to Avoid if You Have Cystic Acne
  8. Products to Use and Avoid if You Have Cystic Acne
  9. Best References and Scientific Publications on Cystic Acne:

This article is for education and is not medical advice. It does not create a doctor-patient relationship. See a board-certified dermatologist for a diagnosis.

Why do I get acne cysts?

Cystic acne occurs in men, women and teenagers. It is most often seen as bumps and cysts along the jawline. These cystic pimples are often recurring. Deep cystic acne can occur anywhere on the face such as the chin, cheeks and forehead or on the body such as the chest, scalp, back and buttocks. What causes cystic acne? Is cystic acne hormonal? What are the best treatments for cystic acne? Before we answer these questions, I will explain what cystic acne is.

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What is Cystic Acne?

A true acne cyst is a clogged hair follicle filled with bacteria that has been walled off by the body's immune system to keep the acne-causing bacteria from spreading. When the body's natural inflammation cycle occurs, the pore gets clogged. This causes a comedone. The closed pore allows pressure to build up inside the hair follicle, stretching out the hair follicle allowing more room for bacteria, pus, keratin and dead keratinocytes. If untreated, the pressure eventually ruptures the wall of the hair follicle leading to scarring.

What is the white stuff that comes out of a cyst?

Acne cysts are filled with white pus. What is in this white liquid in cysts?

The hair follicle is lined with epidermal cells called keratinocytes. These keratinocytes make a protein called keratin. (This is why they are called keratinocytes.)

The thick white smelly stuff in a cyst is keratin. Keratin is the same protein that makes hair and nails.


How cysts form?

When the pore becomes clogged and a closed comedone forms, there is a build up of debris inside the the hair follicle.

The contents of this debris in an acne cyst are :

  • Sebum (oil)
  • Keratin
  • Dead keratinocytes
  • Exudate from immune cells we call pus
  • Acne causing bacteria known as Cutibacterium acnes. (The name was changed from P. acnes to C. acnes)

What Is Cystic Acne?

Cystic acne starts in the hair follicle which opens as a pore on the skin's surface.


The hair follicles get clogged hair with dead skin cells and keratin which causes comedones. Why do the hair follicles get clogged? Click here to read more about this.


When dead skin cells and oil accumulate in the hair follicle, bacteria is attracted to the hair follicle. This triggers inflammation which brings fluid to the area. Accumulation of the inflammatory fluid, desquamated skin cells, and keratin protein further increase the intrafollicular pressure.

The pressure caused by the build up of dead skin cells, pus, and fluids breaks the wall of the hair follicle, allowing bacteria into the skin. The body recognizes this bacteria as foreign and mounts an immune response. Immune cells surround the bacteria and pus and wall it off to prevent spread of infection to other parts of the body. This leads to a cyst.


If you pick at the acne cyst, it can turn into an epidermal inclusion cyst which must be removed by a small surgical procedure. Scarring can also occur with cystic acne because of damage to the walls of the hair follicle.


What causes cystic acne?

Cystic acne in men and women is caused by a combination of these factors:



How to Treat Cystic Acne?

Can you cure cystic acne? Yes but the best way to cure cystic acid is to begin a retinoid. You can try a topical one first, but if you have severe cystic acne you should see a dermatologist because you may need a prescription for an oral retinoid.


The best way to treat cystic acne is to get on the right products for your Baumann Skin Type. Let our dermatologists guide you by choosing products based on your Baumann Skin Type.

What is your Baumann Skin Type?

Find out which of the 16 Baumann Skin Types you are in about 3 minutes, then shop only what's approved for your skin.

Take the quiz

What is your Baumann Skin Type?

Finish the free quiz to find out which ingredients and products are right for your skin.

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Is this right for your skin?

Dr. Baumann already picked the ingredients that are right for your skin type. They are in your routine.

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Vitamins To Use if You Have Cystic Acne

Retinoids are a form of Vitamin A. You can take Vitamin A supplements to treat acne but you must be careful not to take more than 4,000 IU's per day. Vitamin A is a fat soluble vitamin which means it is toxic when too much is taken. Vitamin A can also cause birth defects if taken while pregnant. It is much safer to see a dermatologist to treat your acne cysts then trying to manage it naturally by yourself. Retinoids are a safe way to treat acne cysts but should be carefully monitored by your doctor with blood test that follow your liver function and triglycerides and cholesterol levels.

Vitamins to Avoid if You Have Cystic Acne

If you have cystic acne, avoid Vitamins B6 and Vitamin B12 because they can cause acne breakouts. These acne cyst causing vitamins are in many body building supplements.

Products to Use and Avoid if You Have Cystic Acne

The best way to avoid getting cystic acne is to avoid using products with comedogenic ingredients. You also need to make sure that when you choose skin care products, you shop by your Baumann Skin Type.

What is your Baumann Skin Type?

Find out which of the 16 Baumann Skin Types you are in about 3 minutes, then shop only what's approved for your skin.

Take the quiz

What is your Baumann Skin Type?

Finish the free quiz to find out which ingredients and products are right for your skin.

Finish the quiz

Is this right for your skin?

Dr. Baumann already picked the ingredients that are right for your skin type. They are in your routine.

See my routine
Level up your skin care knowledge with medical advice from dermatologists

Best References and Scientific Publications on Cystic Acne:

  1. Sally, R. Rieder, E. Ch.16 Acne in Baumann's Cosmetic Dermatology (McGraw Hill 2022)
  2. Harris HH, Downing DT, Stewart ME, Strauss JS. Sustainable rates of sebum secretion in acne patients and matched normal control subjects. J Am Acad Dermatol. 1983;8(2):200-203. doi:10.1016/s0190-9622(83)70023-x
  3. Clayton RW, Göbel K, Niessen CM, Paus R, Steensel MAM, Lim X. Homeostasis of the sebaceous gland and mechanisms of acne pathogenesis. Br J Dermatol. 2019;181(4):677-690. doi:10.1111/bjd.17981
  4. Jahns AC, Lundskog B, Ganceviciene R, et al. An increased incidence of Propionibacterium acnes biofilms in acne vulgaris: a case-control study: Increased incidence of P. acnes biofilms in acne vulgaris. Br J Dermatol. 2012;167(1):50-58. doi:10.1111/j.1365-2133.2012.10897.x
  5. Kim J, Ochoa M-T, Krutzik SR, et al. Activation of Toll-Like Receptor 2 in Acne Triggers Inflammatory Cytokine Responses. J Immunol. 2002;169(3):1535-1541. doi:10.4049/jimmunol.169.3.1535




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Dr. Leslie Baumann

Dr. Leslie Baumann, MD, FAAD

Board-certified dermatologist, author and researcher, and creator of the Baumann Skin Type System. A former professor at the University of Miami Miller School of Medicine, where she founded the Cosmetic Dermatology Center in 1997. Author of the New York Times bestseller The Skin Type Solution, Cosmetic Dermatology: Principles and Practice, and Cosmeceuticals and Cosmetic Ingredients.

Have any additional questions? Ask Dr. Baumann on Reddit! r/SkinTypeSolutions Ask on Reddit (opens in a new tab)

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