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HA5 Rejuvenating Hydrator
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Not recommended for your sensitivity
SkinMedica HA5 Rejuvenating Hydrator is a top-selling hyaluronic acid serum that delivers oil-free hydration, smooths fine lines, and enhances your skincare routine.
- Gives skin a dewy glow
- Smooths fine lines quickly
- Skin feels firmer
Why Dr. Baumann carries this
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Approved for Baumann Skin Types
- 3
- 4
- 7
- 8
- 11
- 12
- 15
- 16
Approved for 8 of the 16 Baumann Skin Types, and not for the Allergic sensitive subtype. Dr. Baumann reviews every product against all 16 types before it goes on the site.
What it is and what it does
The SkinMedica HA5 Rejuvenating Hydrator is a top selling, luxury, medical-grade hyaluronic acid serum that delivers oil-free hydration, smooths fine lines, and boosts your routine's effectiveness. Its advanced formula features five distinct forms of hyaluronic acid (HA), each imparting multiple benefits. The tiniest HA molecules penetrate the skin and bind water, restoring plumpness and volume from within, while larger HA particles sit on the skin’s surface, acting as a humectant to attract moisture to the skin's surface and visibly reduce the appearance of fine lines. This gives your skin the dewy, "glass skin" finish that is all the rage right now. This multi-level hydration keeps skin smooth, soft, glowing and radiant all day long.
With a combination of time-released and fast-acting HA forms, this hydrator offers both immediate skin benefits. It improves moisture retention and enhances the absorption and performance of other products in your skincare routine when used in the correct routine step. By maintaining optimal hydration levels, the SkinMedica HA5 Rejuvenating Hydrator prepares your skin to absorb serums and creams more effectively, boosting their overall results.
This lightweight, silky formula is suitable for all skin types, including sensitive, dry, oily, and acne-prone skin. If you have dry skin, this should be used in combination with a barrier repair moisturizer. Oily skin types can use this under sunscreen.
This product is paraben-free, fragrance-free, and oil-free but contains dimethicone.
Who it is for
- Gives skin a dewy glow
- Smooths fine lines quickly
- Skin feels firmer
- Improves overall skin texture
- Boosts the performance of other skincare products
Approved for 8 of the 16 Baumann Skin Types, and not for the Allergic sensitive subtype.
Key ingredients

Glycerin (Glycerol) is the best natural moisturizing ingredient to hydrate skin quickly. May give products a sticky feel.

Attracts water, giving cells and skin volume. Plays a key role in cell signals and other vital processes. It cushions the skin, providing resilience and firmness. This moisturizing humectant temporarily plumps fine lines and wrinkles. HA makes skin feel dewy and look radiant and glowing. Great for oily skin because it feels lightweight and non-greasy on the skin. Safe for all skin types. HA helps other skincare products get into the skin. This antiaging and hydrating ingredient can radically alter how your skin routine works by affecting penetration and absorption of other ingredients- so make sure you use it in the correct step of your skin care routine.

An antioxidant and hydrating ingredient. Stabilizes Vitamin C.

Porphyridium Cruentum Extract, derived from a red microalgae (Porphyridium cruentum), is prized for its moisturizing and anti-aging properties. It contains a high concentration of polysaccharides and essential fatty acids, which help to create a protective barrier on the skin, preventing moisture loss and improving hydration levels. Additionally, this extract is rich in antioxidants, such as vitamins and minerals, that help combat free radical damage, thereby protecting the skin from environmental stressors. Porphyridium cruentum also has anti-inflammatory benefits, which can help calm sensitive or irritated skin. It is often used in skincare to enhance skin firmness, elasticity, and to provide a smoother, more radiant complexion.

Alteromonas Ferment Extract, derived from the marine bacterium Alteromonas species, is known for its moisturizing and protective properties. It works by forming a protective film on the skin, which helps to prevent moisture loss and reinforces the skin's barrier function. Additionally, this extract contains polysaccharides that help to soothe irritated skin and reduce inflammation, making it suitable for sensitive skin types. It may also provide antioxidant benefits, protecting the skin from oxidative stress caused by environmental factors like pollution and UV radiation. Overall, it is used in skincare formulations to promote hydration, calmness, and skin protection.

Vibrio Alginolyticus Ferment Filtrate
Vibrio Alginolyticus Ferment Filtrate, derived from the marine bacterium Vibrio alginolyticus, is primarily used for its skin-soothing and regenerative properties. It contains bioactive compounds that stimulate skin repair and promote cellular renewal, making it particularly useful in anti-aging products. This ferment filtrate is known to boost skin hydration by enhancing the skin barrier function, reducing transepidermal water loss (TEWL). Additionally, it may have antioxidant effects, helping to neutralize free radicals and protect against environmental stressors. Due to these combined properties, it is frequently found in products designed to improve skin elasticity and overall radiance.
Full ingredient list
Product type and skin type data
| Brand | SkinMedica |
|---|---|
| Product type | Facial Treatment |
| Approved Baumann Skin Types | OSPW, OSNW, DSNW, DSPW, ORPW, ORNW, DRPW, DRNW |
| Recommended for these sensitivities | Acne, Redness, Stinging |
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Questions about this product
Answered by Dr. Leslie Baumann, MD, FAAD · Miami, FL · 200+ partner practices
The inclusion of five different types of hyaluronic acid
allows for
multi-level hydration. Smaller HA molecules penetrate deeply to restore
plumpness from within, while larger molecules sit on the surface, acting as a
humectant to lock in moisture. This combination provides immediate and
long-term hydration, smoothing fine lines and creating a glowing, "glass
skin" finish.
Yes, it is worth the price because it's one of the few
hyaluronic acid serums
with five different sizes of HA. Each type offers different benefits, from deep
hydration to surface-level moisture retention, helping to plump the skin,
smooth fine lines, and provide long-lasting hydration.
SkinMedica HA5 features five types of hyaluronic acid of all
different molecular
weights for multi-layer hydration, offering immediate plumping and smoothing.
Alastin HA Immerse uses high-molecular-weight HA, focusing on boosting the
skin’s natural HA production for long-term hydration.
Users frequently mention the deep hydration, lightweight
feel, and how it rapidly
improves skin texture, leaving a glowing, “glass skin” finish.
It temporarily reduces the appearance of fine lines by
plumping the skin,
thanks to its multi-level hydration.
The formula is non-sticky and absorbs quickly into the skin,
making it suitable
for layering under makeup or sunscreen.
People love that it works well under makeup, especially when
combined with
SPF, as it leaves the skin smooth and prepped for foundation.
Many with sensitive and acne-prone skin say they experienced
no breakouts or
irritation, with the product being lightweight and non-comedogenic.
Reviews
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