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TXA Serum
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Nothing in this product works against any of your four letters, so it is safe for your skin type.
Not recommended for your sensitivity
Earn $6 back in Skin Type Cash on purchases of Derma Made TXA Serum! Derma Made TXA Serum (formerly Melafade Serum) is an affordable brightening serum in the battle against uneven skin pigmentation, dark spots, and melasma.
- Blocks pigment production 3 ways
- Lightweight dark spot remover
Why Dr. Baumann carries this
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Approved for Baumann Skin Types
- 1
- 3
- 5
- 7
- 9
- 11
- 13
- 15
Approved for 8 of the 16 Baumann Skin Types, and not for the Allergic sensitive subtype. Dr. Baumann reviews every product against all 16 types before it goes on the site.
What it is and what it does
Earn $6 back in Skin Type Cash on purchases of Derma Made TXA Serum! Derma Made TXA Serum (formerly Melafade Serum) is an affordable brightening serum in the battle against uneven skin pigmentation, dark spots, and melasma. Developed by a dermatologist for her own melasma patients, this bestselling skin lightening serum is specifically formulated to help even out your complexion for a more radiant, luminous look.
The TXA Serum is powered by a potent blend of skin-lightening actives, including 5% Tranexamic Acid, 2% alpha arbutin, and 1% Hexylresorcinol. These ingredients work synergistically to help inhibit melanin production, the pigment responsible for causing dark spots and hyperpigmentation. With regular use, this serum can help fade existing discoloration and prevent new dark spots from forming, leaving you with a more uniform, clarified complexion.
The TXA Serum has a lightweight, fast-absorbing texture that layers seamlessly under moisturizer and makeup. It is free of harsh bleaching agents like hydroquinone, making it a safer, gentler option for those with sensitive skin.
Simply apply a few drops to clean skin every morning and night to kick-start your journey towards brighter, more even-toned skin.
Don't let hyperpigmentation dim your glow. Try Derma Made TXA Serum and unveil your most radiant, even-toned skin yet.
Who it is for
- Blocks pigment production 3 ways
- Lightweight dark spot remover
Approved for 8 of the 16 Baumann Skin Types, and not for the Allergic sensitive subtype.
Key ingredients

Skin lightening ingredient to treat dark spots caused by acne, sun, and light exposure. Used in both treatment and maintenance melasma routines because it's skin lightening effects do not depend upon blocking tyrosinase.

A skin lightener that reduces melanin in skin giving an even skin tone

One of the best dark spot removers in hyperpigmentation creams.
Full ingredient list
Product type and skin type data
| Brand | Derma Made |
|---|---|
| Product type | Facial Treatment |
| Size | 1.0 oz. |
| Item number | DMD-106 |
| Approved Baumann Skin Types | DSPT, DRPW, DRPT, DSPW, ORPW, OSPT, OSPW, ORPT |
| Recommended for these sensitivities | Acne, Redness, Stinging |
Read more from Dr. Baumann
Skincare LibraryBy Dr. Leslie Baumann · 5 min read
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Questions about this product
Answered by Dr. Leslie Baumann, MD, FAAD · Miami, FL · 200+ partner practices
Most users report noticeable improvements within 4 to 8 weeks, depending on the product. Brightening and retinol products may take longer but offer gradual, visible benefits when used consistently.
No. This product has kojic acid which is a derivative of hydroquinone. Choose a product with cysteamine, niacinamide, Vitamin C or other lightening ingredients that are not chemically similar to hydroquinone,
Do not use Melafade is you are having a rosacea flare. There are many strong ingredients in this serum that an worsen the flare. Consider using the Derma Made Azelaic Acid 15% Cream instead. Make sure you know which of the 16 skin types you are so you can make sure you are not making your own rosacea worse by using the wrong skin care products for your skin type.
Derma Made Melafade contains 3% Tranexamic acid.
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